A few fresh leaves are lightly crushed or heated before being applied to the affected area, wrapped in a clean cloth. Application must be brief and never on broken skin. This preparation should only be considered with the advice of a professional familiar with the plant's toxicity. Dosage must be validated with a healthcare professional or recognized pharmacopoeia before use.
A small quantity of dried leaves is brought to a boil then heavily diluted before strictly external use, for example as a local wash or compress. This preparation, due to the plant's toxicity, must be carried out under professional supervision. Dosage must be validated with a healthcare professional or recognized pharmacopoeia before use.
Nicotiana glauca grows spontaneously in arid and disturbed areas, often along roadsides or on vacant lots, in South America as well as in several regions of the Mediterranean basin where it has become naturalized. It is not commercially available in herbal shops due to its recognized toxicity.
The leaves, when they were traditionally harvested, were collected preferably in spring or summer, from plants in full growth, avoiding any prolonged contact with bare skin.