Among the plants of the Sonoran Desert, Aristolochia watsonii, sometimes called "hierba del indio" by the peoples of the American Southwest, held a particular place in traditional Native American and Mexican pharmacopoeias. Its twisted stem and acrid smell made it a plant as feared as it was sought, reserved for precise, limited uses.
The tribes of the Sonoran Desert traditionally used the chewed stem or a poultice on snakebites, while awaiting more effective help. This use, widely documented in regional ethnobotany, has never been scientifically validated as an antidote.
A mild stem decoction was sometimes used in very small amounts to relieve occasional digestive trouble, according to practices reported among certain Native American communities.
The crushed stem or a poultice was traditionally applied to wounds or skin inflammation, as a local external treatment.
Some ethnobotanical sources mention an occasional use of the plant to try to bring down a fever, always in a very diluted preparation.
All Aristolochia species contain aristolochic acid, a substance recognized as nephrotoxic and carcinogenic; their internal use is strongly discouraged and regulated, even banned in several countries. Never use this plant internally without medical advice or that of a practitioner qualified in plant toxicology. Contraindicated during pregnancy and breastfeeding because of proven risks to the kidneys and fetal development. Prolonged or repeated use, even at a low dose, can cause serious, irreversible kidney damage; do not repeat doses without strict supervision.
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PFAF, Wikipedia